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Chandler, Ariz.—March 7, 2008— Thousands of people are changing their lives and striving to be healthy, clean and lean during the second annual IsaBody Challenge™, hosted by Isagenix®, the world leader in nutritional cleansing™.

The Challenge, which began in February and continues through June 15, 2008 for U.S., Canadian and Puerto Rican Associates, encourages participants to transform their bodies and lives through nutritional cleansing and Isagenix supplements. In addition to improving their health and wellness, participants stand to win their share of more than $100,000 in cash prizes. A separate Challenge is also being held in Australia/New Zealand and Hong Kong.

“The IsaBody Challenge™ is a great incentive to set and achieve your health and wellness goals by following an Isagenix system,” says Isagenix President and CEO Jim Coover. “We’ve been able to impact thousands of lives with this Challenge and will help thousands more this year.”

The Challenge is open to anyone 18 years of age and older who follows an Isagenix system on their path to greater health. Challenge participants can enter in one of seven categories including Men and Women ages 18 to 39, 40 to 59, 60 and over, and a first-ever family category. All first through third place winners in each category will also win a trip to Las Vegas in August to attend the 2008 “Commitment to Greatness” Celebration.

More than 2,200 people committed to greater health by participating in the inaugural IsaBody Challenge™ last year and made significant changes to their body and lifestyle. In the end, 25 lucky winners lost a combined 1,000* pounds and took home $100,000 in cash and prizes. Last year’s winners experienced more than just sheer weight loss. They rediscovered their zest for life, conquered unhealthy eating habits, boosted self-esteem, regained athleticism, built muscle and took up sports and fitness activities they had abandoned or never knew were possible.